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Search parameters (2023.01)

Comet search parameters are defined here. These are valid for Comet version 2023.01.X.

Parameters for all versions of Comet can be found here. Entries marked with an * are new parameters. Entries marked with an ** are modified parameters.

To generate a comet.params file appropriate for your Comet binary, issue the command “comet -p”.

Example comet.params files (primary differences are the MS and MS/MS mass tolerance settings):


CPU threads


Search enzyme

Fragment ions


mzXML/mzML parameters

Misc. parameters

Spectral processing

Variable modifications

Static modifications